Basic Information
ID: ALA5115324
Type: Binding
Description: Selectivity ratio of IC50 for inhibition of Bcr-Abl T315I mutant (unknown origin) to IC50 for inhibition of wild type Bcr-Abl (unknown origin)
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA5115324
Ratio IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 493.62 | 4.59 | 4.59 |
| 609.03 | 5.39 | 5.39 |
| 442.46 | 2.35 | 2.35 |
| 576.99 | 4.51 | 4.51 |
| 505.89 | 3.68 | 3.68 |
| 532.91 | 3.99 | 3.99 |
| 590.99 | 5.27 | 5.27 |
| 550.97 | 2.85 | 2.85 |
| 551.96 | 4.78 | 4.78 |
| 575.48 | 5.03 | 5.03 |
| 519.92 | 3.90 | 3.90 |
| 527.41 | 3.21 | 3.21 |
| 508.92 | 3.75 | 3.75 |
| 490.88 | 3.62 | 3.62 |
| 535.41 | 3.47 | 3.47 |
| 535.06 | 2.74 | 2.74 |
| 517.40 | 3.76 | 3.76 |
| 558.95 | 4.38 | 4.38 |
| 485.37 | 2.84 | 2.84 |
| 549.94 | 3.03 | 3.03 |
| 457.33 | 3.25 | 3.25 |
| 519.92 | 3.45 | 3.45 |
| 493.88 | 3.51 | 3.51 |
| 557.44 | 4.90 | 4.90 |
| 510.53 | 3.12 | 3.12 |
| 585.49 | 4.48 | 4.48 |
| 484.49 | 2.73 | 2.73 |
| 509.37 | 3.08 | 3.08 |
| 525.40 | 4.02 | 4.02 |
| 535.96 | 4.54 | 4.54 |
| 567.45 | 4.36 | 4.36 |
| 451.84 | 3.14 | 3.14 |
| 467.33 | 2.71 | 2.71 |
| 550.95 | 4.12 | 4.12 |
| 543.44 | 4.15 | 4.15 |
| 499.36 | 3.63 | 3.63 |
| 542.57 | 4.00 | 4.00 |
| 475.37 | 3.38 | 3.38 |
| 553.45 | 3.60 | 3.60 |
| 535.96 | 4.04 | 4.04 |
| 529.93 | 2.93 | 2.93 |