Basic Information
ID: ALA5115428
Type: ADME
Description: Inhibition of CYP450 in Sprague-Dawley rat liver microsomes assessed as inhibition of 20-HETE formation in presence of arachidonic acid and NADPH by multi-enzyme assay based LC-MS/MS analysis relative to control
Organism: Rattus norvegicus
Strain: Sprague-Dawley
Tissue: Liver
Subcellular Fraction: Microsome
Activity Charts
Bioactivity
Activity Types for Assay ALA5115428
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 290.24 | 4.48 | 4.48 |