Basic Information
ID: ALA5115450
Type: ADME
Description: Inhibition of CYP2D6 in human kidney microsomes assessed as inhibition of 20-HETE formation using 3-[2-(N,N-diethyl-N-methyl-amino)ethyl]-7-methoxy-4-methyl-coumarin as substrate in presence of arachidonic acid and NADPH by fluorescence assay
Organism: Homo sapiens
Tissue: Kidney
Subcellular Fraction: Microsome
Activity Charts
Bioactivity
Activity Types for Assay ALA5115450
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 206.29 | 2.98 | 2.98 |
| 255.71 | 2.01 | 2.01 |