Assay Report Card

Basic Information

ID: ALA5115804

Type: Binding

Description: Protac activity at CRBN/EGFR L858R/T790M mutant in human NCI-H1975 cells assessed as L858R/T790M mutant degradation at 3 uM incubated for 48 hrs by Western blot analysis

Organism: Homo sapiens

Cell type: NCI-H1975

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
869.863.873.87
882.864.974.97
868.875.455.45
910.915.755.75
856.864.774.77