Assay Report Card

Basic Information

ID: ALA5115809

Type: Binding

Description: Protac activity at CRBN/EGFR L858R/T790M mutant in human NCI-H1975 cells assessed as L858R/T790M mutant degradation at 0.03 to 3 uM incubated for 48 hrs by Western blot analysis relative to untreated control

Organism: Homo sapiens

Cell type: NCI-H1975

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
883.894.214.21