Basic Information
ID: ALA5115882
Type: Binding
Description: Inhibition of human recombinant ALKBH5 (66 to 292 residues) expressed in Escherichia coli BL21 (DE3) cells using FAM-labeled ssRNA (5'-CUCGAUACG(m^6A) UCCGGUCAAA-3') as substrate incubated for 60 mins by fluorescence polarization assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA5115882
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 309.35 | 0.93 | 0.93 |
| 389.41 | 2.43 | 2.43 |
| 405.41 | 2.03 | 2.03 |
| 476.56 | 3.15 | 3.15 |
| 297.11 | 2.35 | 2.35 |
| 361.33 | 1.22 | 1.22 |
| 222.18 | 1.42 | 1.42 |
| 351.08 | 3.06 | 3.06 |
| 418.45 | 1.70 | 1.70 |
| 364.43 | 0.91 | 0.91 |
| 282.28 | 0.68 | 0.68 |
| 238.63 | 1.93 | 1.93 |
| 339.37 | 0.80 | 0.80 |
| 234.21 | 1.28 | 1.28 |
| 405.41 | 2.03 | 2.03 |
| 371.42 | 2.29 | 2.29 |
| 406.51 | 1.94 | 1.94 |
| 387.42 | 1.99 | 1.99 |
| 283.08 | 2.04 | 2.04 |
| 335.39 | 1.50 | 1.50 |
| 297.11 | 2.35 | 2.35 |
| 311.32 | 0.33 | 0.33 |
| 377.45 | 2.35 | 2.35 |
| 283.08 | 2.04 | 2.04 |
| 401.44 | 2.30 | 2.30 |
| 325.35 | 0.63 | 0.63 |
| 234.21 | 1.28 | 1.28 |
| 218.21 | 1.58 | 1.58 |
| 229.19 | 1.15 | 1.15 |
| 246.27 | 2.40 | 2.40 |
| 338.39 | 0.38 | 0.38 |
| 238.63 | 1.93 | 1.93 |
| 325.35 | 0.41 | 0.41 |
| 272.18 | 2.29 | 2.29 |
| 311.32 | 0.33 | 0.33 |
| 350.40 | 0.52 | 0.52 |
| 256.62 | 2.07 | 2.07 |
| 323.37 | 1.18 | 1.18 |
| 405.41 | 2.03 | 2.03 |
| 232.24 | 1.89 | 1.89 |
| 311.32 | 0.33 | 0.33 |
| 272.18 | 2.29 | 2.29 |
| 351.38 | 1.20 | 1.20 |
| 286.21 | 2.60 | 2.60 |
| 389.41 | 2.43 | 2.43 |
| 204.19 | 1.28 | 1.28 |
| 288.18 | 2.17 | 2.17 |
| 218.21 | 1.58 | 1.58 |
| 405.86 | 2.94 | 2.94 |
| 283.08 | 2.04 | 2.04 |
| 272.18 | 2.29 | 2.29 |