Basic Information
ID: ALA5116616
Type: Binding
Description: Potentiation of homozygous CFTR F508del mutant in human HBE cells assessed as maximal activation by trans-epithelial current clamp assay relative to ABBV-2222
Organism: Homo sapiens
Cell type: HBE
Activity Charts
Bioactivity
Activity Types for Assay ALA5116616
%max
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 561.65 | 5.85 | 5.85 |
| 527.11 | 6.09 | 6.09 |
| 548.77 | 6.73 | 6.73 |
| 547.74 | 6.10 | 6.10 |
| 550.74 | 5.72 | 5.72 |
| 506.69 | 6.17 | 6.17 |
| 663.78 | 6.01 | 6.01 |
| 534.74 | 6.56 | 6.56 |
| 570.77 | 6.48 | 6.48 |
| 549.76 | 6.13 | 6.13 |
| 536.72 | 5.32 | 5.32 |
| 648.85 | 5.63 | 5.63 |
| 626.88 | 7.90 | 7.90 |