Basic Information
ID: ALA5117148
Type: Binding
Description: Inhibition of topoisomerase 1 (unknown origin) assessed as relaxation of supercoiled plasmid pBR322 DNA at 10 uM incubated for 45 mins by ethidium bromide staining based agarose gel electrophoresis
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA5117148
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 348.36 | 2.08 | 2.08 |
| 434.97 | 5.40 | 5.40 |
| 410.86 | 4.54 | 4.54 |
| 499.04 | 4.73 | 4.73 |
| 421.93 | 5.48 | 5.48 |
| 463.03 | 6.17 | 6.17 |
| 395.89 | 4.98 | 4.98 |
| 463.03 | 6.18 | 6.18 |
| 420.94 | 5.05 | 5.05 |
| 497.04 | 6.97 | 6.97 |
| 477.05 | 6.57 | 6.57 |
| 379.85 | 4.74 | 4.74 |
| 449.00 | 5.79 | 5.79 |
| 462.98 | 5.31 | 5.31 |
| 396.87 | 5.02 | 5.02 |
| 496.01 | 6.55 | 6.55 |
| 424.88 | 5.20 | 5.20 |
| 395.89 | 5.05 | 5.05 |
| 521.06 | 6.70 | 6.70 |
| 410.90 | 5.67 | 5.67 |
| 415.90 | 4.29 | 4.29 |