Basic Information
ID: ALA5117307
Type: Binding
Description: Inhibition of N-terminal His/SUMO tagged recombinant SARS-CoV2 main protease expressed in Escherichia coli BL21 (DE3) cells using DABCYL-Lys-Thr-Ser-Ala-Val-Leu-Gln-Ser-Gly-Phe-Arg-Lys-MetGlu-EDANS as substrate preincubated with enzyme for 30 mins followed by substrate addition and measured after 30 mins by fluorescence based assay
Format: BAO_0000219
Organism: Severe acute respiratory syndrome coronavirus 2
Target: Replicase polyprotein 1ab(ALA4523582)
Document: ALA5113464
Inhibition of N-terminal His/SUMO tagged recombinant SARS-CoV2 main protease expressed in Escherichia coli BL21 (DE3) cells using DABCYL-Lys-Thr-Ser-Ala-Val-Leu-Gln-Ser-Gly-Phe-Arg-Lys-MetGlu-EDANS as substrate preincubated with enzyme for 30 mins followed by substrate addition and measured after 30 mins by fluorescence based assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA5117307
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 600.76 | 3.15 | 3.15 |
| 502.61 | 1.68 | 1.68 |
| 560.69 | 2.23 | 2.23 |
| 536.63 | 1.87 | 1.87 |
| 542.68 | 2.60 | 2.60 |
| 594.71 | 2.42 | 2.42 |