Selectivity index, ratio of CC50 for cytotoxicity against HEK293T/17 cells by MTT assay to EC50 for antiviral activity against SARS-Cov2 USA-WA1/2020 ...

Basic Information

ID: ALA5117308

Type: Toxicity

Description: Selectivity index, ratio of CC50 for cytotoxicity against HEK293T/17 cells by MTT assay to EC50 for antiviral activity against SARS-Cov2 USA-WA1/2020 infected in African green monkey Vero E6 cells assessed as viral plaque reduction by plaque reduction neutralization test

Format: BAO_0000219

Target:  ADMET(ALA612558)

Document:  ALA5113464

Selectivity index, ratio of CC50 for cytotoxicity against HEK293T/17 cells by MTT assay to EC50 for antiviral activity against SARS-Cov2 USA-WA1/2020 infected in African green monkey Vero E6 cells assessed as viral plaque reduction by plaque reduction neutralization test: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
600.763.153.15
558.681.981.98
574.722.622.62
530.672.462.46