Basic Information
ID: ALA5117929
Type: Binding
Description: Inhibition of EGFR del18/T790M/C797S triple mutant (unknown origin) using TK as substrate incubated for 120 mins in the presence of ATP by HTRF assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA5117929
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 584.11 | 5.09 | 5.09 |
| 695.60 | 5.92 | 5.92 |
| 708.65 | 5.70 | 5.70 |
| 722.67 | 6.09 | 6.09 |
| 694.62 | 5.45 | 5.45 |
| 701.60 | 5.61 | 5.61 |
| 714.65 | 5.53 | 5.53 |
| 701.60 | 5.75 | 5.75 |
| 714.65 | 5.67 | 5.67 |
| 714.65 | 5.67 | 5.67 |
| 684.58 | 4.89 | 4.89 |
| 701.60 | 5.75 | 5.75 |
| 715.63 | 5.86 | 5.86 |
| 698.61 | 5.14 | 5.14 |
| 698.61 | 5.28 | 5.28 |
| 700.62 | 5.49 | 5.49 |
| 710.61 | 6.13 | 6.13 |
| 715.63 | 6.14 | 6.14 |
| 700.62 | 5.28 | 5.28 |
| 711.65 | 5.19 | 5.19 |