Assay Report Card

Basic Information

ID: ALA5117985

Type: Binding

Description: Invivo inhibition of ERK phosphorylation in nude mouse implanted with mouse BaF3 cells harboring EGFR del18/T790M/C797S triple mutant at 20 mg/kg, po administered as single dose and measured upto 24 hrs by Western blot analysis

Organism: Mus musculus

Cell type: BaF3

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
701.605.615.61