Assay Report Card

Basic Information

ID: ALA5117989

Type: Functional

Description: Antitumor activity against human PC-9 cells harboring EGFR del18/T790M/C797S triple mutant xenografted in NOD/SCID mouse assessed as tumor growth inhibition at 40 mg/kg, po administered once a day for 21 days relative to control

Organism: Homo sapiens

Cell type: PC-9

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
701.605.615.61