Basic Information
ID: ALA5118352
Type: Functional
Description: Antagonist activity at human OX1R expressed in CHO-K1 cells assessed as inhibition of orexin-A-induced increase in calcium mobilization preincubated for 15 mins followed orexin-A stimulation by Fura-2-AM dye based fluorescence assay
Organism: Homo sapiens
Cell type: CHO-K1
Activity Charts
Bioactivity
Activity Types for Assay ALA5118352
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 621.69 | 5.71 | 5.71 |
| 647.78 | 5.82 | 5.82 |
| 621.69 | 5.71 | 5.71 |
| 647.78 | 5.82 | 5.82 |
| 621.69 | 5.71 | 5.71 |
| 561.64 | 5.69 | 5.69 |
| 563.61 | 4.48 | 4.48 |
| 563.61 | 4.48 | 4.48 |
| 563.61 | 4.48 | 4.48 |
| 563.61 | 4.48 | 4.48 |
| 647.78 | 5.82 | 5.82 |
| 647.78 | 5.82 | 5.82 |
| 409.53 | 3.32 | 3.32 |
| 647.78 | 5.82 | 5.82 |
| 563.61 | 4.48 | 4.48 |
| 621.69 | 5.71 | 5.71 |
| 591.66 | 5.70 | 5.70 |
| 621.69 | 5.71 | 5.71 |
| 561.64 | 5.69 | 5.69 |
| 633.75 | 4.79 | 4.79 |
| 553.66 | 5.88 | 5.88 |
| 563.61 | 4.48 | 4.48 |
| 591.66 | 5.70 | 5.70 |
| 621.69 | 5.71 | 5.71 |
| 621.69 | 5.71 | 5.71 |
| 647.78 | 5.82 | 5.82 |