Basic Information
ID: ALA5118545
Type: Binding
Description: Inhibition of FLT3-ITD mutant (unknown origin) at 1 uM preincubated with compound for 10 mins followed by substrate addition and measured after 1 hrs by ADP-Glo kinase assay relative to control
Format: BAO_0000357
Organism: Homo sapiens
Target: Tyrosine-protein kinase receptor FLT3(ALA1974)
Document: ALA5113503
Inhibition of FLT3-ITD mutant (unknown origin) at 1 uM preincubated with compound for 10 mins followed by substrate addition and measured after 1 hrs by ADP-Glo kinase assay relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA5118545
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 375.41 | 4.90 | 4.90 |
| 461.83 | 6.10 | 6.10 |
| 481.43 | 5.18 | 5.18 |
| 427.46 | 4.09 | 4.09 |
| 447.88 | 4.81 | 4.81 |
| 431.43 | 4.30 | 4.30 |
| 449.49 | 3.92 | 3.92 |
| 428.45 | 4.55 | 4.55 |
| 427.46 | 4.47 | 4.47 |
| 413.44 | 4.16 | 4.16 |
| 405.46 | 3.14 | 3.14 |
| 413.44 | 4.16 | 4.16 |
| 441.49 | 4.48 | 4.48 |
| 428.45 | 4.55 | 4.55 |
| 492.33 | 4.92 | 4.92 |
| 427.46 | 4.09 | 4.09 |
| 443.46 | 4.17 | 4.17 |