Basic Information
ID: ALA5118572
Type: Binding
Description: Inhibition of C-terminal His tagged SARS CoV-2 main protease transfected in Escherichia coli BL21 (DE3) using 2-Abz-Ser-AlaVal-Leu-Gln-Ser-Gly-Tyr(3-NO2)-Arg-OH as substrate preincubated for 15 mins followed by substrate addition and measured after 15 mins by FRET assay
Organism: Severe acute respiratory syndrome coronavirus 2
Activity Charts
Bioactivity
Activity Types for Assay ALA5118572
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 133.94 | ||
| 151.93 | ||
| 519.69 | 1.71 | 1.71 |
| 239.68 | 3.02 | 3.02 |
| 321.06 | ||
| 268.08 | ||
| 148.96 | ||
| 178.94 | ||
| 393.63 | ||
| 361.21 | ||
| 347.18 | ||
| 323.57 | ||
| 337.59 | ||
| 247.10 | ||
| 358.21 | ||
| 345.16 | ||
| 264.09 | ||
| 428.08 | ||
| 352.13 | ||
| 360.18 | ||
| 283.09 | ||
| 373.22 | ||
| 338.17 | ||
| 393.63 | ||
| 359.19 | ||
| 373.22 | ||
| 384.20 | ||
| 359.19 | ||
| 345.16 | ||
| 310.12 | ||
| 359.19 | ||
| 372.19 | ||
| 389.22 | ||
| 283.09 | ||
| 365.24 | ||
| 191.00 | ||
| 268.08 |