Assay Report Card

Basic Information

ID: ALA5118577

Type: Binding

Description: Potency index, ratio of boceprevir IC50 to test compound IC50 for inhibition of C-terminal His tagged SARS CoV-2 main protease transfected in Escherichia coli BL21 (DE3) using 2-Abz-Ser-AlaVal-Leu-Gln-Ser-Gly-Tyr(3-NO2)-Arg-OH as substrate preincubated for 15 mins followed by substrate addition and measured after 15 mins by FRET assay

Organism: Severe acute respiratory syndrome coronavirus 2

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
359.19