Basic Information
ID: ALA5119231
Type: Functional
Description: Positive allosteric modulation of human D1R expressed in SK-N-MC cells assessed as inhibition of DA-induced cAMP production pretreated with compound for 15 mins followed by dopamine EC70 addition measured after 15 mins by HTRF assay
Organism: Homo sapiens
Cell type: SK-N-MC
Activity Charts
Bioactivity
Activity Types for Assay ALA5119231
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 313.78 | 4.35 | 4.35 |
| 230.24 | 3.47 | 3.47 |
| 279.34 | 3.69 | 3.69 |
| 264.32 | 3.40 | 3.40 |
| 278.35 | 3.79 | 3.79 |
| 246.31 | 4.19 | 4.19 |
| 280.32 | 3.06 | 3.06 |
| 244.26 | 3.86 | 3.86 |
| 248.23 | 3.77 | 3.77 |
| 260.26 | 3.45 | 3.45 |
| 293.36 | 4.08 | 4.08 |
| 230.24 | 3.47 | 3.47 |
| 295.34 | 2.57 | 2.57 |
| 246.24 | 3.36 | 3.36 |
| 280.32 | 3.09 | 3.09 |
| 264.30 | 4.48 | 4.48 |
| 248.23 | 3.77 | 3.77 |
| 313.78 | 4.35 | 4.35 |
| 230.24 | 3.47 | 3.47 |
| 281.31 | 2.31 | 2.31 |
| 245.25 | 2.76 | 2.76 |
| 248.23 | 3.77 | 3.77 |
| 293.36 | 3.75 | 3.75 |
| 230.24 | 3.47 | 3.47 |
| 248.23 | 3.77 | 3.77 |