Basic Information
ID: ALA5119452
Type: Binding
Description: Inhibition of NLRP3 inflammasome activation in LPS-primed mouse J774.A1 cells assessed as reduction in IL-1beta secretion preincubated for 1 hr followed by nigericin stimulation and measured after 1 hr by ELISA
Organism: Mus musculus
Cell type: J774.A1
Activity Charts
Bioactivity
Activity Types for Assay ALA5119452
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 384.25 | ||
| 383.26 | ||
| 361.03 | ||
| 404.49 | 2.99 | 2.99 |
| 451.16 | ||
| 451.16 | ||
| 418.25 | ||
| 417.14 | ||
| 446.74 | ||
| 303.98 | ||
| 398.27 | ||
| 430.29 | ||
| 487.21 | ||
| 434.31 | ||
| 501.22 | ||
| 418.25 | ||
| 384.44 | 1.43 | 1.43 |
| 418.25 | ||
| 437.13 | ||
| 434.70 | ||
| 451.16 | ||
| 452.15 | ||
| 451.16 | ||
| 391.06 | ||
| 418.25 | ||
| 375.06 | ||
| 403.12 | ||
| 417.14 | ||
| 437.13 | ||
| 467.16 | ||
| 451.35 | 3.95 | 3.95 |