Basic Information
ID: ALA5119580
Type: Binding
Description: Inhibition of CDK8 (unknown origin) at 200 nM incubated in presence of ATP by ADP-Glo kinase assay relative to control
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA5119580
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 464.83 | 5.55 | 5.55 |
| 395.89 | 3.40 | 3.40 |
| 450.61 | 3.23 | 3.23 |
| 443.86 | 5.87 | 5.87 |
| 443.86 | 6.47 | 6.47 |
| 409.41 | 5.82 | 5.82 |
| 377.39 | 5.08 | 5.08 |
| 422.45 | 6.73 | 6.73 |
| 355.44 | 5.11 | 5.11 |
| 427.40 | 5.96 | 5.96 |
| 375.86 | 4.86 | 4.86 |
| 413.44 | 5.54 | 5.54 |
| 341.41 | 4.80 | 4.80 |
| 427.40 | 5.96 | 5.96 |
| 439.44 | 5.83 | 5.83 |
| 375.86 | 5.45 | 5.45 |
| 433.86 | 5.88 | 5.88 |
| 371.44 | 4.81 | 4.81 |
| 377.39 | 5.08 | 5.08 |
| 425.41 | 5.57 | 5.57 |
| 424.43 | 5.52 | 5.52 |
| 409.41 | 5.82 | 5.82 |
| 449.48 | 6.38 | 6.38 |
| 370.46 | 4.90 | 4.90 |
| 373.43 | 5.25 | 5.25 |
| 413.44 | 5.69 | 5.69 |
| 438.45 | 5.92 | 5.92 |
| 439.44 | 6.25 | 6.25 |
| 387.87 | 5.84 | 5.84 |
| 359.40 | 4.34 | 4.34 |
| 394.48 | 5.29 | 5.29 |
| 521.59 | 5.57 | 5.57 |
| 386.46 | 4.60 | 4.60 |
| 423.44 | 6.13 | 6.13 |
| 377.39 | 5.08 | 5.08 |
| 457.88 | 6.78 | 6.78 |
| 425.45 | 5.62 | 5.62 |
| 423.44 | 6.13 | 6.13 |
| 377.39 | 5.08 | 5.08 |
| 502.33 | 6.89 | 6.89 |
| 429.83 | 6.08 | 6.08 |
| 469.46 | 5.19 | 5.19 |
| 424.43 | 5.52 | 5.52 |
| 359.40 | 4.94 | 4.94 |
| 373.43 | 4.62 | 4.62 |
| 374.42 | 4.73 | 4.73 |
| 442.42 | 5.75 | 5.75 |
| 355.44 | 4.51 | 4.51 |
| 424.43 | 5.61 | 5.61 |
| 442.42 | 5.75 | 5.75 |
| 442.42 | 5.75 | 5.75 |
| 375.86 | 5.45 | 5.45 |
| 409.41 | 5.74 | 5.74 |
| 356.43 | 4.59 | 4.59 |
| 369.47 | 5.36 | 5.36 |
| 477.41 | 6.84 | 6.84 |
| 370.46 | 4.27 | 4.27 |
| 454.45 | 5.62 | 5.62 |
| 305.38 | 3.30 | 3.30 |
| 367.45 | 5.50 | 5.50 |
| 374.42 | 4.73 | 4.73 |
| 359.40 | 4.94 | 4.94 |
| 371.44 | 4.81 | 4.81 |
| 424.43 | 5.61 | 5.61 |
| 370.46 | 4.90 | 4.90 |
| 331.38 | 3.80 | 3.80 |
| 359.40 | 4.34 | 4.34 |
| 434.42 | 5.69 | 5.69 |
| 421.42 | 6.21 | 6.21 |
| 341.41 | 4.20 | 4.20 |
| 457.88 | 6.78 | 6.78 |
| 423.44 | 5.53 | 5.53 |
| 455.87 | 6.86 | 6.86 |
| 409.41 | 5.22 | 5.22 |
| 399.42 | 5.23 | 5.23 |
| 439.41 | 6.35 | 6.35 |
| 551.61 | 5.95 | 5.95 |
| 537.59 | 5.56 | 5.56 |
| 347.46 | 4.47 | 4.47 |
| 424.43 | 5.10 | 5.10 |
| 383.50 | 5.92 | 5.92 |
| 371.44 | 4.21 | 4.21 |
| 355.44 | 5.11 | 5.11 |
| 549.33 | 6.73 | 6.73 |
| 458.87 | 6.27 | 6.27 |
| 359.40 | 4.94 | 4.94 |
| 427.40 | 5.96 | 5.96 |
| 441.48 | 6.29 | 6.29 |
| 427.40 | 5.96 | 5.96 |
| 377.39 | 5.08 | 5.08 |
| 409.41 | 5.82 | 5.82 |
| 417.41 | 5.37 | 5.37 |
| 390.87 | 5.25 | 5.25 |
| 355.44 | 4.48 | 4.48 |