Basic Information
ID: ALA5119587
Type: Binding
Description: Inhibition of CDK8 in human HCT-116 cells transfected with TOPFlash luciferase reporter plasmid assessed as reduction in TCF/LEF transcriptional activity
Organism: Homo sapiens
Cell type: HCT-116
Activity Charts
Bioactivity
Activity Types for Assay ALA5119587
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 464.83 | 5.55 | 5.55 |
| 395.89 | 3.40 | 3.40 |
| 450.61 | 3.23 | 3.23 |
| 443.86 | 6.47 | 6.47 |
| 355.44 | 5.11 | 5.11 |
| 375.86 | 5.45 | 5.45 |
| 373.43 | 5.25 | 5.25 |
| 521.59 | 5.57 | 5.57 |
| 423.44 | 6.13 | 6.13 |
| 377.39 | 5.08 | 5.08 |
| 434.42 | 5.69 | 5.69 |
| 409.41 | 5.22 | 5.22 |
| 383.50 | 5.92 | 5.92 |