Basic Information
ID: ALA5119594
Type: Binding
Description: Inhibition of CDK8 in human HaCaT cells assessed as reduction in TGF-beta induced SMAD3 phosphorylation at thr179 residue pretreated with compound for 30 mins followed by TGF-beta treatment for 16 hrs by Western blot assay
Organism: Homo sapiens
Cell type: HaCaT
Activity Charts
Bioactivity
Activity Types for Assay ALA5119594
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 423.44 | 6.13 | 6.13 |