Basic Information
ID: ALA5120161
Type: Binding
Description: Antagonist activity at human P2X7 receptor expressed in HEK293 cells assessed as reduction in YO-PRO-1 iodide dye uptake preincubated for 30 mins followed by YO-PRO-1 iodide addition and measured after 120 mins by fluorescence plate reader analysis
Organism: Homo sapiens
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA5120161
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 360.53 | 3.35 | 3.35 |
| 381.51 | 3.15 | 3.15 |
| 388.58 | 4.13 | 4.13 |
| 360.53 | 3.35 | 3.35 |
| 389.57 | 2.50 | 2.50 |
| 386.57 | 3.88 | 3.88 |
| 400.59 | 4.13 | 4.13 |
| 431.65 | 3.67 | 3.67 |
| 381.51 | 3.15 | 3.15 |
| 382.49 | 2.55 | 2.55 |
| 388.54 | 2.73 | 2.73 |
| 375.54 | 2.11 | 2.11 |