Basic Information
ID: ALA5120384
Type: Functional
Description: Inhibition of human DOR expressed in CHO cells assessed as reduction in Leu-enkephalin induced ERK1/2 phosphorylation level by measuring Leu-enkephalin pEC50 measured after 1 hr by fluorescence based AlphaScreen assay
Organism: Homo sapiens
Cell type: CHO
Activity Charts
Bioactivity
Activity Types for Assay ALA5120384
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 470.61 | 6.97 | 6.97 |
| 535.48 | 7.43 | 7.43 |
| 498.66 | 7.79 | 7.79 |
| 434.58 | 6.27 | 6.27 |
| 448.60 | 6.66 | 6.66 |
| 434.58 | 6.27 | 6.27 |
| 496.65 | 7.54 | 7.54 |
| 488.60 | 7.11 | 7.11 |
| 480.60 | 6.65 | 6.65 |
| 471.60 | 6.37 | 6.37 |
| 484.64 | 7.23 | 7.23 |