Assay Report Card

Basic Information

ID: ALA5120386

Type: Functional

Description: Inhibition of human DOR expressed in CHO cells assessed as reduction in Leu-enkephalin induced cAMP level by measuring Leu-enkephalin pEC50 measured after 5 mins by BRET assay

Organism: Homo sapiens

Cell type: CHO

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
470.616.976.97
535.487.437.43
498.667.797.79
434.586.276.27
448.606.666.66
434.586.276.27
496.657.547.54
488.607.117.11
480.606.656.65
471.606.376.37
484.647.237.23