Basic Information
ID: ALA5120624
Type: Binding
Description: Inhibition of JAK1/JAK3 in human primary T-cells assessed as reduction of IL-2 stimulated STAT5 phosphorylation preincubated for 1 hr followed by IL-2 stimulation for 15 mins by FACS method
Organism: Homo sapiens
Cell type: T-cell
Activity Charts
Bioactivity
Activity Types for Assay ALA5120624
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 395.39 | 4.16 | 4.16 |
| 412.43 | 2.35 | 2.35 |
| 395.39 | 4.18 | 4.18 |
| 431.37 | 4.73 | 4.73 |
| 426.46 | 3.08 | 3.08 |
| 454.51 | 3.03 | 3.03 |
| 398.40 | 2.05 | 2.05 |
| 358.36 | 3.58 | 3.58 |
| 412.43 | 2.35 | 2.35 |
| 377.40 | 4.02 | 4.02 |
| 411.44 | 3.11 | 3.11 |
| 407.43 | 4.03 | 4.03 |
| 391.43 | 4.33 | 4.33 |
| 426.46 | 2.36 | 2.36 |
| 425.47 | 2.10 | 2.10 |
| 411.44 | 3.11 | 3.11 |
| 431.37 | 4.73 | 4.73 |
| 439.50 | 2.11 | 2.11 |
| 423.43 | 3.73 | 3.73 |
| 358.36 | 3.58 | 3.58 |
| 416.39 | 2.18 | 2.18 |
| 393.40 | 3.72 | 3.72 |
| 411.45 | 2.09 | 2.09 |
| 426.46 | 2.36 | 2.36 |
| 442.53 | 3.54 | 3.54 |
| 419.34 | 4.86 | 4.86 |
| 412.43 | 2.35 | 2.35 |
| 426.46 | 3.08 | 3.08 |
| 426.46 | 2.25 | 2.25 |
| 432.49 | 2.85 | 2.85 |
| 419.45 | 2.94 | 2.94 |
| 462.44 | 2.84 | 2.84 |
| 413.38 | 4.65 | 4.65 |