Basic Information
ID: ALA5121012
Type: Binding
Description: Inhibition of recombinant human N-terminal His6-SUMO-tagged C-terminal SII-tagged HDAC4 expressed in Escherichia coli (BL21) DE3 pLysS cells using BocLys(trifluoroacetyl)-AMC as substrate incubated for 30 mins by fluorescence assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA5121012
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 537.52 | 5.18 | 5.18 |
| 537.52 | 5.18 | 5.18 |
| 491.50 | 4.50 | 4.50 |
| 515.57 | 5.21 | 5.21 |
| 509.49 | 4.64 | 4.64 |
| 570.43 | 6.21 | 6.21 |
| 517.99 | 5.42 | 5.42 |
| 562.45 | 5.53 | 5.53 |
| 501.54 | 4.91 | 4.91 |
| 551.55 | 5.79 | 5.79 |
| 501.54 | 4.91 | 4.91 |
| 552.44 | 6.07 | 6.07 |
| 519.53 | 5.05 | 5.05 |
| 533.56 | 5.35 | 5.35 |
| 519.53 | 5.05 | 5.05 |
| 569.54 | 5.93 | 5.93 |
| 535.98 | 5.56 | 5.56 |
| 497.58 | 5.08 | 5.08 |
| 483.55 | 4.77 | 4.77 |