Basic Information
ID: ALA5121095
Type: Functional
Description: Reversal of 5-FU resistance against 5-FU resistant DPD expressed human HCT-116 cells assessed as reduction in cell viability incubated for 48 hrs in presence of 5-FU by MTT assay
Organism: Homo sapiens
Cell type: HCT-116
Activity Charts
Bioactivity
Activity Types for Assay ALA5121095
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 408.29 | 4.25 | 4.25 |
| 466.47 | 3.95 | 3.95 |
| 394.27 | 3.77 | 3.77 |
| 472.34 | 4.80 | 4.80 |
| 496.28 | 5.50 | 5.50 |
| 547.21 | 4.71 | 4.71 |
| 448.36 | 5.17 | 5.17 |
| 446.27 | 4.62 | 4.62 |
| 445.29 | 5.23 | 5.23 |
| 432.27 | 4.39 | 4.39 |
| 406.28 | 4.00 | 4.00 |
| 403.42 | 3.47 | 3.47 |
| 560.60 | 5.83 | 5.83 |
| 482.78 | 5.51 | 5.51 |
| 412.38 | 4.20 | 4.20 |
| 423.86 | 3.84 | 3.84 |
| 495.97 | 5.02 | 5.02 |
| 481.94 | 4.63 | 4.63 |
| 394.27 | 3.94 | 3.94 |
| 441.85 | 3.98 | 3.98 |
| 462.26 | 4.79 | 4.79 |
| 380.24 | 3.44 | 3.44 |
| 483.94 | 5.15 | 5.15 |
| 482.95 | 4.82 | 4.82 |
| 462.26 | 4.96 | 4.96 |
| 442.31 | 4.79 | 4.79 |
| 473.87 | 4.32 | 4.32 |
| 460.30 | 4.93 | 4.93 |
| 453.89 | 3.85 | 3.85 |
| 458.31 | 4.49 | 4.49 |
| 481.94 | 4.63 | 4.63 |
| 428.28 | 4.49 | 4.49 |
| 408.29 | 4.08 | 4.08 |
| 456.34 | 4.72 | 4.72 |