Basic Information
ID: ALA5121796
Type: Functional
Description: Invivo inhibition of FGFR3 phosphorylation in human NIH/3T3 cells overexpressing FGFR3 S249C xenografted in Balb/c nude mouse at 30 mg/kg, po administered as single dose and measured after 6 hrs by sandwich ELISA analysis relative to control
Format: BAO_0000218
Organism: Mus musculus
Strain: Balb/c
Target: Unchecked(ALA612545)
Document: ALA5120772
Invivo inhibition of FGFR3 phosphorylation in human NIH/3T3 cells overexpressing FGFR3 S249C xenografted in Balb/c nude mouse at 30 mg/kg, po administered as single dose and measured after 6 hrs by sandwich ELISA analysis relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA5121796
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 407.38 | 2.28 | 2.28 |
| 584.67 | 4.32 | 4.32 |
| 612.94 | 2.97 | 2.97 |
| 584.88 | 2.20 | 2.20 |