Basic Information
ID: ALA5121856
Type: Binding
Description: Inhibition of wild type N-terminal GST tagged FGFR3 (436 to 806 residues) (unknown origin) expressed in sf21 insect cells preincubated for 30 mins followed by substrate addition and measured after 30 mins in presence of ATP by off-chip mobility shift assay
Organism: Homo sapiens
Cell type: Sf21
Activity Charts
Bioactivity
Activity Types for Assay ALA5121856
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 407.38 | 2.28 | 2.28 |
| 584.67 | 4.32 | 4.32 |
| 501.53 | 3.86 | 3.86 |
| 598.70 | 4.71 | 4.71 |
| 756.59 | 5.30 | 5.30 |
| 556.62 | 3.10 | 3.10 |
| 555.63 | 3.71 | 3.71 |
| 499.56 | 4.06 | 4.06 |
| 582.70 | 4.53 | 4.53 |
| 585.66 | 3.71 | 3.71 |
| 612.94 | 2.97 | 2.97 |
| 584.88 | 2.20 | 2.20 |
| 572.63 | 4.45 | 4.45 |
| 568.67 | 4.62 | 4.62 |