Basic Information
ID: ALA5121922
Type: Binding
Description: Inhibition of human Kv1.3 expressed in HEK293 cells assessed as inhibition of tetracyclin induced current at 1 uM at holding potential of -80 mV by patch clamp method relative to control
Format: BAO_0000219
Organism: Homo sapiens
Cell type: HEK293
Target: Voltage-gated potassium channel subunit Kv1.3(ALA4633)
Document: ALA5120778
Inhibition of human Kv1.3 expressed in HEK293 cells assessed as inhibition of tetracyclin induced current at 1 uM at holding potential of -80 mV by patch clamp method relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA5121922
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 600.71 | 4.17 | 4.17 |
| 584.71 | 4.96 | 4.96 |
| 540.65 | 4.60 | 4.60 |
| 645.75 | 5.86 | 5.86 |
| 540.65 | 4.60 | 4.60 |
| 584.71 | 4.96 | 4.96 |
| 540.65 | 4.60 | 4.60 |
| 598.69 | 4.14 | 4.14 |
| 600.71 | 4.67 | 4.67 |
| 496.60 | 4.38 | 4.38 |
| 598.69 | 4.29 | 4.29 |
| 556.65 | 3.72 | 3.72 |
| 556.65 | 3.72 | 3.72 |
| 498.62 | 4.03 | 4.03 |
| 618.72 | 3.13 | 3.13 |
| 645.75 | 5.86 | 5.86 |
| 512.60 | 3.35 | 3.35 |
| 598.69 | 4.14 | 4.14 |
| 626.74 | 5.53 | 5.53 |
| 642.74 | 4.65 | 4.65 |