Assay Report Card

Basic Information

ID: ALA5122130

Type: Binding

Description: Inhibition of P-gp-mediated rhodamine-123 efflux in human COLO 320 cells assessed as fluorescence activity ratio at 20 uM preincubated for 10 mins followed by rhodamine-123 addition and measured after 20 mins by flow cytometry (Rvb = 0.828 No_unit)

Organism: Homo sapiens

Cell type: COLO 320

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
676.895.535.53
478.766.946.94
674.875.745.74
688.905.835.83