Basic Information
ID: ALA5122305
Type: Binding
Description: Inhibition of NLRP3 inflammasome activation in LPS-primed mouse BMDM cells assessed as reduction in LPS/ATP induced cleaved IL-1beta release in supernatant at 10 uM preincubated for 30 mins followed by LPS addition for 3 hrs prior to ATP addition for 30 mins by Western blot analysis
Organism: Mus musculus
Cell type: BMDM
Activity Charts
Bioactivity
Activity Types for Assay ALA5122305
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 404.49 | 2.99 | 2.99 |
| 561.11 | 4.93 | 4.93 |
| 511.09 | 4.83 | 4.83 |
| 454.98 | 3.40 | 3.40 |
| 469.01 | 3.66 | 3.66 |
| 545.11 | 5.23 | 5.23 |
| 567.20 | 6.34 | 6.34 |
| 493.03 | 3.66 | 3.66 |
| 559.13 | 5.27 | 5.27 |
| 575.13 | 5.24 | 5.24 |