Basic Information
ID: ALA5122306
Type: Binding
Description: Inhibition of NLRP3 inflammasome activation in LPS-primed mouse BMDM cells assessed as reduction in LPS/ATP induced cleaved IL-1beta release in supernatant at 2 uM preincubated for 30 mins followed by LPS addition for 3 hrs prior to ATP addition for 30 mins by Western blot analysis
Organism: Mus musculus
Cell type: BMDM
Activity Charts
Bioactivity
Activity Types for Assay ALA5122306
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 497.06 | 4.57 | 4.57 |
| 420.54 | 2.74 | 2.74 |
| 424.96 | 3.39 | 3.39 |