Basic Information
ID: ALA5122530
Type: Functional
Description: Potentiation of adriamycin-induced cytotoxicity in human MCF7 cells harbouring wild type BRCA1/2 assessed as inhibition of cell growth at 25 uM incubated for 48 hrs in presence of 0.8 uM adriamycin by MTT assay relative to control
Format: BAO_0000219
Organism: Homo sapiens
Cell type: MCF7
Target: MCF7(ALA387)
Document: ALA5120815
Potentiation of adriamycin-induced cytotoxicity in human MCF7 cells harbouring wild type BRCA1/2 assessed as inhibition of cell growth at 25 uM incubated for 48 hrs in presence of 0.8 uM adriamycin by MTT assay relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA5122530
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 434.47 | 2.35 | 2.35 |
| 484.54 | 3.24 | 3.24 |
| 514.61 | 4.27 | 4.27 |
| 542.66 | 5.05 | 5.05 |
| 500.53 | 2.48 | 2.48 |
| 515.59 | 2.64 | 2.64 |
| 527.60 | 2.78 | 2.78 |
| 513.58 | 2.39 | 2.39 |