Basic Information
ID: ALA5122536
Type: Binding
Description: Inhibition of PARP-1 in human MCF7 cells assessed as inhibition of PARylation by measuring reduction in PARP protein expression at 1 uM pretreated with adriamycin followed by compound addition and measured after 48 hrs by Western bot analysis
Format: BAO_0000219
Organism: Homo sapiens
Cell type: MCF7
Target: Poly [ADP-ribose] polymerase-1(ALA3105)
Document: ALA5120815
Inhibition of PARP-1 in human MCF7 cells assessed as inhibition of PARylation by measuring reduction in PARP protein expression at 1 uM pretreated with adriamycin followed by compound addition and measured after 48 hrs by Western bot analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA5122536
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 500.53 | 2.48 | 2.48 |