Basic Information
ID: ALA5122842
Type: Functional
Description: Inhibition of androstenedione induced testosterone production in human 22Rv1 cells expressing AKR1C3 assessed as reduction in testosterone level to 0.5 uM pretreated for 1 hr followed by androstenedione addition and measured after 24 hrs by ELISA relative to control
Format: BAO_0000219
Organism: Homo sapiens
Cell type: CWR22R
Target: Unchecked(ALA612545)
Document: ALA5120830
Inhibition of androstenedione induced testosterone production in human 22Rv1 cells expressing AKR1C3 assessed as reduction in testosterone level to 0.5 uM pretreated for 1 hr followed by androstenedione addition and measured after 24 hrs by ELISA relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA5122842
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 400.44 | 3.96 | 3.96 |