Potency index, ratio of allopurinol IC50 to test compound IC50 for inhibition of bovine XOD assessed as inhibition of uric acid formation using xanthi...

Basic Information

ID: ALA5123189

Type: Binding

Description: Potency index, ratio of allopurinol IC50 to test compound IC50 for inhibition of bovine XOD assessed as inhibition of uric acid formation using xanthine as substrate preincubated with enzyme for 5 mins followed by substrate addition and measured for 30 mins by microplate reader analysis

Format: BAO_0000357

Organism: Bos taurus

Target:  Xanthine dehydrogenase(ALA3649)

Document:  ALA5120838

Potency index, ratio of allopurinol IC50 to test compound IC50 for inhibition of bovine XOD assessed as inhibition of uric acid formation using xanthine as substrate preincubated with enzyme for 5 mins followed by substrate addition and measured for 30 mins by microplate reader analysis: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
684.651.961.96
648.621.021.02
650.591.081.08
788.604.014.01