Basic Information
ID: ALA5123438
Type: Binding
Description: Protac activity at CRBN E3 ligase/FAK in human A549 cells assessed as induction of FAK protein degradation at 0.1 uM incubated for 12 hrs by Western blot analysis relative to control
Organism: Homo sapiens
Cell type: A549
Activity Charts
Bioactivity
Activity Types for Assay ALA5123438
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 468.95 | 3.82 | 3.82 |
| 896.41 | 3.53 | 3.53 |
| 823.31 | 4.32 | 4.32 |
| 880.41 | 4.30 | 4.30 |
| 809.33 | 4.68 | 4.68 |
| 865.39 | 5.49 | 5.49 |
| 908.46 | 5.08 | 5.08 |
| 894.43 | 4.69 | 4.69 |
| 912.40 | 2.77 | 2.77 |
| 936.52 | 5.86 | 5.86 |
| 851.37 | 5.10 | 5.10 |
| 941.54 | 6.51 | 6.51 |
| 879.42 | 5.88 | 5.88 |
| 899.41 | 3.67 | 3.67 |
| 908.46 | 5.08 | 5.08 |
| 866.38 | 3.91 | 3.91 |
| 837.34 | 4.71 | 4.71 |
| 969.59 | 7.29 | 7.29 |
| 823.31 | 4.32 | 4.32 |
| 893.45 | 6.27 | 6.27 |