Assay Report Card

Basic Information

ID: ALA5123525

Type: Binding

Description: Inhibition of FLT3-mediated signalling pathway in human MOLM-14 cells harboring FLT3 ITD/D835Y double mutant assessed as reduction in FLT3 protein stability at 3 to 30 nM incubated for 16 hrs by Western blot analysis

Organism: Homo sapiens

Cell type: MOLM-14

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
439.901.631.63