Assay Report Card

Basic Information

ID: ALA5123530

Type: Functional

Description: Antitumor activity against human MOLM-14 cells harboring FLT3 ITD/D835Y double mutant xenografted in NOD-SCID mouse assessed as reduction in tumor growth at 10 mg/kg, ip administered 6 days per week for 30 days starting from 4 days post inoculation

Organism: Homo sapiens

Cell type: MOLM-14

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
439.901.631.63