Assay Report Card

Basic Information

ID: ALA5123531

Type: Toxicity

Description: Toxicity in NOD-SCID mouse xenografted with human MOLM-14 cells harboring FLT3 ITD/D835Y double mutant assessed as body weight loss at 10 mg/kg, ip administered 6 days per week for 30 days starting from 4 days post inoculation

Organism: Mus musculus

Cell type: MOLM-14

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
439.901.631.63