Assay Report Card

Basic Information

ID: ALA5123550

Type: Binding

Description: Inhibition of recombinant human SENP1 assessed as reduction in deSUMOylation of RanGAP1-SUMO1 at 5 uM using RanGAP1-SUMO1 as substrate preincubated for 10 mins followed by substrate addition and measured after 30 mins relative to control

Organism: Homo sapiens

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
456.717.097.09
472.716.066.06
456.717.097.09
470.696.276.27
488.715.185.18
488.715.185.18
442.737.007.00
488.715.035.03
472.716.206.20
502.694.354.35
456.717.097.09
488.715.185.18
488.715.185.18
472.716.066.06
488.715.185.18
484.686.076.07
440.718.288.28
504.714.154.15
504.714.154.15
456.717.097.09