Basic Information
ID: ALA5123561
Type: Binding
Description: Inhibition of human N-terminal 6His-tagged PARP15 (460 to 656 residues) expressed in Escherichia coli Rosetta2 (DE3) cells using NAD+ as substrate incubated for 10 mins by fluorescence based analysis
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA5123561
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 347.17 | 2.56 | 2.56 |
| 340.42 | 3.72 | 3.72 |
| 275.28 | 2.51 | 2.51 |
| 307.35 | 3.53 | 3.53 |
| 233.31 | 2.74 | 2.74 |
| 333.43 | 1.25 | 1.25 |
| 232.24 | 1.01 | 1.01 |
| 274.32 | 2.18 | 2.18 |
| 223.25 | 2.10 | 2.10 |
| 234.28 | 1.82 | 1.82 |
| 263.34 | 2.75 | 2.75 |
| 324.15 | 3.27 | 3.27 |
| 205.26 | 1.96 | 1.96 |
| 246.27 | 1.40 | 1.40 |
| 260.29 | 1.79 | 1.79 |
| 275.28 | 2.51 | 2.51 |
| 336.18 | 3.14 | 3.14 |
| 191.23 | 1.57 | 1.57 |
| 251.30 | 2.88 | 2.88 |
| 286.26 | 1.93 | 1.93 |
| 274.30 | 1.86 | 1.86 |
| 219.28 | 2.35 | 2.35 |