Assay Report Card

Basic Information

ID: ALA5123617

Type: Binding

Description: Inhibition of GO/LDHA in hyperoxaluric-primary hepatocyte isolated from Agxt1 knockdown PH1 C57BL/6 mouse assessed as reduction in extracellular oxalate concentration at 10 uM measured at 48 hrs in the presence of glycolate relative to control

Organism: Mus musculus

Strain: C57BL/6

Cell type: Hepatocyte

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
232.192.162.16
504.635.155.15
288.302.072.07
371.353.873.87