Basic Information
ID: ALA5123694
Type: Binding
Description: Inhibition of human p300 HAT domain (1195 to 1673 residues) at 10 uM using histone H3 peptide and acetyl-coA as substrates preincubated for 10 mins followed by substrate addition and measured after 30 mins by beckman scintillation counting analysis relative to control
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA5123694
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 503.24 | 5.71 | 5.71 |
| 395.47 | 3.93 | 3.93 |
| 449.35 | 4.82 | 4.82 |
| 449.35 | 4.82 | 4.82 |
| 405.50 | 3.17 | 3.17 |
| 459.64 | 4.31 | 4.31 |
| 499.62 | 6.31 | 6.31 |
| 463.17 | 5.06 | 5.06 |
| 491.23 | 5.67 | 5.67 |
| 449.15 | 4.67 | 4.67 |
| 414.34 | 5.50 | 5.50 |
| 481.44 | 6.23 | 6.23 |
| 405.50 | 4.21 | 4.21 |
| 499.62 | 6.31 | 6.31 |
| 491.18 | 4.85 | 4.85 |
| 661.03 | 7.24 | 7.24 |
| 463.17 | 4.93 | 4.93 |
| 434.09 | 5.03 | 5.03 |
| 517.27 | 6.23 | 6.23 |
| 491.23 | 5.71 | 5.71 |
| 401.55 | 5.31 | 5.31 |
| 489.21 | 5.32 | 5.32 |
| 477.20 | 5.45 | 5.45 |