Basic Information
ID: ALA5123995
Type: Functional
Description: Antileishmanial activity against intracellular Leishmania infantum MHOM/MA(BE)/67 ITMAP263 amastigotes infected in Swiss mouse peritoneal macrophage assessed as inhibition of parasite growth measured after 5 days by geimsa staining based microscopic analysis
Organism: Leishmania infantum
Strain: MHOM/MA(BE)/67 ITMAP263
Cell type: Peritoneal macrophage
Activity Charts
Bioactivity
Activity Types for Assay ALA5123995
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 407.58 | 5.68 | 5.68 |
| 136.11 | 0.06 | 0.06 |
| 331.33 | 0.61 | 0.61 |
| 347.40 | 1.08 | 1.08 |
| 347.40 | 1.08 | 1.08 |
| 381.39 | 1.76 | 1.76 |
| 342.36 | 0.41 | 0.41 |
| 343.34 | -0.19 | -0.19 |
| 376.80 | 1.07 | 1.07 |
| 371.39 | 1.03 | 1.03 |
| 330.34 | 0.35 | 0.35 |
| 356.38 | 0.60 | 0.60 |
| 380.40 | 1.28 | 1.28 |
| 386.36 | 0.93 | 0.93 |
| 372.38 | 0.42 | 0.42 |
| 392.42 | 1.57 | 1.57 |
| 393.80 | 1.81 | 1.81 |
| 368.39 | 0.92 | 0.92 |
| 375.81 | 1.67 | 1.67 |
| 373.43 | 1.50 | 1.50 |
| 370.41 | 0.53 | 0.53 |
| 342.36 | 0.41 | 0.41 |
| 360.35 | 0.55 | 0.55 |
| 380.40 | 1.50 | 1.50 |
| 405.84 | 1.68 | 1.68 |
| 392.42 | 1.57 | 1.57 |
| 394.43 | 1.51 | 1.51 |
| 409.36 | 2.04 | 2.04 |
| 387.46 | 1.74 | 1.74 |
| 376.80 | 1.07 | 1.07 |
| 347.37 | 0.15 | 0.15 |
| 431.45 | 2.92 | 2.92 |
| 343.34 | -0.19 | -0.19 |
| 356.38 | 0.60 | 0.60 |
| 419.46 | 0.42 | 0.42 |
| 331.33 | -0.26 | -0.26 |
| 376.80 | 1.07 | 1.07 |
| 376.80 | 1.07 | 1.07 |
| 376.80 | 1.07 | 1.07 |
| 342.36 | 0.41 | 0.41 |
| 359.36 | 1.16 | 1.16 |
| 392.42 | 1.57 | 1.57 |
| 343.34 | -0.19 | -0.19 |
| 348.38 | 0.47 | 0.47 |
| 375.81 | 1.67 | 1.67 |
| 345.36 | -0.25 | -0.25 |