Basic Information
ID: ALA5124002
Type: Functional
Description: Antitrypanosomal activity against nifurtimox-sensitive Tulahuen CL2 amastigotes expressing beta galactosidase infected in human MRC5 cells assessed as inhibition of parasite growth using chlorophenol red beta-D-galactopyranoside as substrate and measured after 7 days by spectrophotometric analysis
Organism: Trypanosoma cruzi
Strain: Tulahuen CL2
Cell type: MRC5
Activity Charts
Bioactivity
Activity Types for Assay ALA5124002
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 260.25 | 1.11 | 1.11 |
| 342.36 | 0.41 | 0.41 |
| 330.34 | 0.35 | 0.35 |
| 380.40 | 1.28 | 1.28 |
| 392.42 | 1.57 | 1.57 |
| 380.40 | 1.50 | 1.50 |
| 376.80 | 1.07 | 1.07 |
| 343.34 | -0.19 | -0.19 |
| 376.80 | 1.07 | 1.07 |
| 376.80 | 1.07 | 1.07 |
| 343.34 | -0.19 | -0.19 |
| 348.38 | 0.47 | 0.47 |