Assay Report Card

Basic Information

ID: ALA5124348

Type: Functional

Description: Antiinflammatory activity in LPS-induced mouse RAW264.7 cells assessed as enhancement of JAK2 phosphorylation at 0.2 to 5 uM pretreated with alpha7 nAChR antagonist alpha-bungarotoxin for 1 hr followed by compound treatment for 2 hrs and further stimulated with LPS for 30 mins by Western blot analysis

Organism: Mus musculus

Cell type: RAW264.7

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
426.514.814.81
366.414.274.27