Assay Report Card

Basic Information

ID: ALA5124519

Type: Binding

Description: Protac activity at VHL/BCL-XL in human MOLT-4 cells assessed as decrease in BCL-XL protein level by measuring maximum degradation at 1 uM pretreated with MG132 for 1 hr followed by compound addition and measured after 6 hrs by immunoblot analysis relative to control

Organism: Homo sapiens

Cell type: MOLT-4

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
1528.36